Heptamidine dimethanesulfonate ( SBi4211 dimethanesulfonate )

Catalog No. M23716 CAS No. 161374-55-6

Heptamidine dimethanesulfonate is a potent Pentamidine-related inhibitor of the calcium-binding protein S100B (Kd: 6.9 μM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	192	In Stock
10MG	312	In Stock
25MG	530	In Stock
50MG	758	In Stock
100MG	1044	In Stock
500MG	2097	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Heptamidine dimethanesulfonate
Note

Research use only, not for human use.
Brief Description

Heptamidine dimethanesulfonate is a potent Pentamidine-related inhibitor of the calcium-binding protein S100B (Kd: 6.9 μM).
Description

Heptamidine dimethanesulfonate is a potent Pentamidine-related inhibitor of the calcium-binding protein S100B (Kd: 6.9 μM), selectively kills melanoma cells with S100B over those without S100B.?Heptamidine is a useful tool for the investigation of Myotonic dystrophy (DM).
Synonyms

SBi4211 dimethanesulfonate
Pathway

Others
Target

Other Targets
Recptor

calcium-binding protein S100B
Research Area

——
Indication

——

Chemical Information

CAS Number

161374-55-6
Formula Weight

560.7
Molecular Formula

C23H36N4O8S2
Purity

>98% (HPLC)
Solubility

DMSO:62.5 mg/mL (111.47 mM; Need ultrasonic)
SMILES

N=C(C1=CC=C(OCCCCCCCOC2=CC=C(C(N)=N)C=C2)C=C1)N.CS(=O)(O)=O.CS(=O)(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.McKnight LE, et al. Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B. ACS Med Chem Lett.?2012?Dec 13;3(12):975-979. Epub?2012?Sep 25.

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