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Heptamidine dimethanesulfonate

CAS No. 161374-55-6

Heptamidine dimethanesulfonate ( SBi4211 dimethanesulfonate )

Catalog No. M23716 CAS No. 161374-55-6

Heptamidine dimethanesulfonate is a potent Pentamidine-related inhibitor of the calcium-binding protein S100B (Kd: 6.9 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Heptamidine dimethanesulfonate
  • Note
    Research use only, not for human use.
  • Brief Description
    Heptamidine dimethanesulfonate is a potent Pentamidine-related inhibitor of the calcium-binding protein S100B (Kd: 6.9 μM).
  • Description
    Heptamidine dimethanesulfonate is a potent Pentamidine-related inhibitor of the calcium-binding protein S100B (Kd: 6.9 μM), selectively kills melanoma cells with S100B over those without S100B.?Heptamidine is a useful tool for the investigation of Myotonic dystrophy (DM).
  • Synonyms
    SBi4211 dimethanesulfonate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    calcium-binding protein S100B
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    161374-55-6
  • Formula Weight
    560.7
  • Molecular Formula
    C23H36N4O8S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:62.5 mg/mL (111.47 mM; Need ultrasonic)
  • SMILES
    N=C(C1=CC=C(OCCCCCCCOC2=CC=C(C(N)=N)C=C2)C=C1)N.CS(=O)(O)=O.CS(=O)(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.McKnight LE, et al. Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B. ACS Med Chem Lett.?2012?Dec 13;3(12):975-979. Epub?2012?Sep 25.
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